Evolutionary analysis of TATA-less proximal promoter function
نویسندگان
چکیده
منابع مشابه
Evolutionary analysis of TATA-less proximal promoter function.
Many molecular studies describe how components of the proximal promoter affect transcriptional processes. However, these studies do not account for the likely effects of distant enhancers or chromatin structure, and thus it is difficult to conclude that the sequence variation in proximal promoters acts to modulate transcription in the natural context of the whole genome. This problem, the biolo...
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The availability of sequence specificities for a substantial fraction of yeast's transcription factors and comparative genomic algorithms for binding site prediction has made it possible to comprehensively annotate transcription factor binding sites genome-wide. Here we use such a genome-wide annotation for comprehensively studying promoter architecture in yeast, focusing on the distribution of...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 1999
ISSN: 0737-4038,1537-1719
DOI: 10.1093/oxfordjournals.molbev.a026102